Premium Melanotan 1 (Afamelanotide) Research Peptide UK

Welcome to the highest standard of synthetic peptides. For laboratories and academic researchers looking to buy Melanotan 1 UK supplies, GB Peptides offers strictly tested, highly purified Afamelanotide for advanced in-vitro studies. If you are procuring Melanotan 1 UK for melanocortin receptor research, our batch-tested vials provide reliable consistency from sequence to sequence.

Melanotan 1 (often referred to by its clinical designation Afamelanotide) is a synthetic, full-length tridecapeptide analog of the naturally occurring alpha-melanocyte-stimulating hormone ($\alpha$-MSH).

Mechanism of Action: MC1R Agonism and Photoprotection

When evaluating Melanotan 1 UK in biochemical research models, its specific receptor binding profile is essential to understand. Unlike Melanotan 2, which acts broadly across multiple melanocortin receptors, Melanotan 1 is a highly selective agonist primarily targeting the melanocortin-1 receptor (MC1R).

1. MC1 Receptor (MC1R): Expressed primarily on melanocytes, activation of MC1R stimulates the production of eumelanin (brown/black pigment) over pheomelanin (red/yellow pigment).

2. Cellular Photoprotection: By inducing eumelanin synthesis, Melanotan 1 mimics the body’s natural physiological response to UV radiation, enhancing cellular defense mechanisms against UV-induced damage and oxidative stress.

In modern clinical research, the administration of this synthetic analog is heavily studied for its protective effects against phototoxicity, particularly in models related to light-intolerant conditions such as erythropoietic protoporphyria (EPP).

For foundational clinical data on how this peptide interacts with cellular pigmentation pathways, consult the PubMed clinical review on Afamelanotide and EPP. To explore its broader role in MC1R agonism and photoprotection, review this NCBI publication on melanocortin analogs.

Melanotan 1 Product Specifications

To ensure accuracy and replicability in your laboratory environments, our Melanotan 1 UK stock adheres to strict molecular standards. Every batch undergoes rigorous third-party High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) testing to guarantee $\ge$99% purity.

• Chemical Name: Melanotan I (Afamelanotide)

• Sequence: Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2

• Molecular Formula: $C_{78}H_{111}N_{21}O_{19}$

• Molecular Weight: $1646.8\text{ g/mol}$

• Purity (HPLC): $\ge$99.0%

• Appearance: White lyophilized solid (freeze-dried powder)

• Format: 10mg glass vial

Preparation and Storage Guidelines

Proper storage of Melanotan 1 UK is essential to maintain structural stability. The lyophilized powder is highly stable at room temperature for transit but must be correctly handled upon arrival at your research facility.

• Storage (Lyophilized): Store unmixed vials in a freezer at -20°C (or below) for long-term stability up to 24 months. Avoid repeated freeze-thaw cycles.

• Reconstitution: Prior to research applications, the peptide must be reconstituted using sterile bacteriostatic water. Gently roll the vial until fully dissolved; do not shake aggressively, as this can break the delicate peptide bonds.

• Storage (Reconstituted): Once reconstituted, the solution must be kept refrigerated at 2°C to 8°C and utilized within 30 days to prevent degradation.

Mandatory Research Disclaimer

Please read carefully before purchasing:

This Melanotan 1 UK product is sold exclusively for strictly controlled in-vitro and laboratory research purposes. This product is not a drug, supplement, food, or cosmetic, and it is absolutely NOT intended for human consumption or diagnostic use.

By purchasing from GB Peptides, you agree that you are a qualified researcher, and this product will be handled in compliance with all relevant UK health and safety regulations. We reserve the right to cancel any order if we suspect the product will be used outside of a sanctioned research environment.