Premium PT-141 (Bremelanotide) Research Peptide UK
Welcome to the highest standard of synthetic peptides. For laboratories and academic researchers looking to buy PT-141 UK supplies, GB Peptides offers strictly tested, highly purified Bremelanotide for advanced in-vitro studies. If you are procuring PT-141 UK for melanocortin receptor research, our batch-tested vials provide reliable consistency from sequence to sequence.
PT-141 (often referred to by its clinical designation Bremelanotide) is a synthetic cyclic heptapeptide analog of alpha-melanocyte-stimulating hormone ($\alpha$-MSH), originally developed as a derivative of Melanotan II.
Mechanism of Action: Melanocortin Receptor Agonist
When evaluating PT-141 UK in biochemical research models, its unique receptor binding profile is essential to understand. Bremelanotide acts as a potent, non-selective agonist of the melanocortin receptors, specifically interacting with MC3R and MC4R pathways within the central nervous system.
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MC4 Receptor (MC4R): Central to the regulation of metabolic energy expenditure, feeding behavior, and physiological sexual arousal.
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MC3 Receptor (MC3R): Associated with energy homeostasis and inflammatory responses.
Unlike phosphodiesterase type 5 (PDE5) inhibitors that primarily alter local vascular tissue, Bremelanotide targets the central nervous system. By activating MC4R in the hypothalamus, it stimulates psychogenic pathways. In modern clinical research, administration of this synthetic analog has been extensively studied for its systemic effects on hypoactive sexual desire disorder (HSDD) models, as well as its secondary effects on caloric intake and weight management.
For foundational clinical data on how this peptide interacts with central neural pathways, consult the PubMed clinical review on Bremelanotide. To explore its broader role in metabolic energy expenditure and thermogenesis, review this NCBI publication on MC4R agonism and weight.
PT-141 Product Specifications
To ensure accuracy and replicability in your laboratory environments, our PT-141 UK stock adheres to strict molecular standards. Every batch undergoes rigorous third-party High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) testing to guarantee $\ge$99% purity.
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Chemical Name: Bremelanotide (PT-141)
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Molecular Formula: $C_{50}H_{68}N_{14}O_{10}$
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Molecular Weight: $1025.2\text{ g/mol}$
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Purity (HPLC): $\ge$99.0%
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Appearance: White lyophilized solid (freeze-dried powder)
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Format: 10mg glass vial
Preparation and Storage Guidelines
Proper storage of PT-141 UK is essential to maintain structural stability. The lyophilized powder is highly stable at room temperature for transit but must be correctly handled upon arrival at your research facility.
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Storage (Lyophilized): Store unmixed vials in a freezer at -20°C (or below) for long-term stability up to 24 months. Avoid repeated freeze-thaw cycles.
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Reconstitution: Prior to research applications, the peptide must be reconstituted using sterile bacteriostatic water. Gently roll the vial until fully dissolved; do not shake aggressively, as this can break the delicate peptide bonds.
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Storage (Reconstituted): Once reconstituted, the solution must be kept refrigerated at 2°C to 8°C and utilized within 30 days to prevent degradation.
Mandatory Research Disclaimer
Please read carefully before purchasing:
This PT-141 UK product is sold exclusively for strictly controlled in-vitro and laboratory research purposes. This product is not a drug, supplement, food, or cosmetic, and it is absolutely NOT intended for human consumption or diagnostic use.
By purchasing from GB Peptides, you agree that you are a qualified researcher, and this product will be handled in compliance with all relevant UK health and safety regulations. We reserve the right to cancel any order if we suspect the product will be used outside of a sanctioned research environment.
