Premium Tesamorelin (GHRH Analogue) Research Peptide UK
Welcome to the highest standard of synthetic peptides. For laboratories and academic researchers looking to buy Tesamorelin UK supplies, GB Peptides offers strictly tested, highly purified GHRH analogues for advanced in-vitro studies. If you are procuring Tesamorelin UK for growth hormone and metabolic research, our batch-tested vials provide reliable consistency from sequence to sequence.
Tesamorelin is a synthetic 44-amino-acid polypeptide analogue of the naturally occurring growth hormone-releasing hormone (GHRH). The N-terminal portion of the molecule has been modified with a trans-3-hexenoic acid group to improve its stability, pharmacokinetics, and resistance to cleavage compared to native GHRH.
Mechanism of Action: GHRH Receptor Agonism
When evaluating Tesamorelin UK in biochemical research models, its specific receptor binding profile is essential to understand. Tesamorelin acts as a potent, stable agonist of the GHRH receptors located in the pituitary gland.
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GHRH Receptor Activation: Tesamorelin binds to and activates GHRH receptors, stimulating the synthesis and release of endogenous growth hormone (GH).
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Lipolysis and IGF-1 Modulation: The released GH acts on hepatocytes to stimulate the production of insulin-like growth factor-1 (IGF-1). In clinical research models, this pathway regulates body composition primarily through increased lipolysis, leading to a significant, dose-dependent reduction in visceral adipose tissue and triglycerides.
In modern clinical research, the administration of this synthetic analog is heavily studied for its effects on visceral adiposity, particularly in models related to HIV-associated lipodystrophy and broader metabolic insulin resistance.
For foundational clinical data on how this peptide interacts with metabolic pathways, consult the PubMed clinical review on Tesamorelin and Lipodystrophy. To explore its broader role in GH release and lipid metabolism, review this NCBI publication on GHRH analogues.
Tesamorelin Product Specifications
To ensure accuracy and replicability in your laboratory environments, our Tesamorelin UK stock adheres to strict molecular standards. Every batch undergoes rigorous third-party High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) testing to guarantee $\ge$99% purity.
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Chemical Name: Tesamorelin (trans-3-hexenoyl-GHRH)
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Molecular Formula: $C_{221}H_{366}N_{72}O_{67}S$
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Molecular Weight: $5135.86\text{ g/mol}$
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Purity (HPLC): $\ge$99.0%
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Appearance: White lyophilized solid (freeze-dried powder)
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Format: 2mg glass vial
Preparation and Storage Guidelines
Proper storage of Tesamorelin UK is essential to maintain structural stability. The lyophilized powder is highly stable at room temperature for transit but must be correctly handled upon arrival at your research facility.
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Storage (Lyophilized): Store unmixed vials in a freezer at -20°C (or below) for long-term stability up to 24 months. Avoid repeated freeze-thaw cycles.
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Reconstitution: Prior to research applications, the peptide must be reconstituted using sterile bacteriostatic water. Gently roll the vial until fully dissolved; do not shake aggressively, as this can break the delicate peptide bonds.
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Storage (Reconstituted): Once reconstituted, the solution must be kept refrigerated at 2°C to 8°C and utilized within 30 days to prevent degradation.
Mandatory Research Disclaimer
Please read carefully before purchasing:
This Tesamorelin UK product is sold exclusively for strictly controlled in-vitro and laboratory research purposes. This product is not a drug, supplement, food, or cosmetic, and it is absolutely NOT intended for human consumption or diagnostic use.
By purchasing from GB Peptides, you agree that you are a qualified researcher, and this product will be handled in compliance with all relevant UK health and safety regulations. We reserve the right to cancel any order if we suspect the product will be used outside of a sanctioned research environment.
